Searchable abstracts of presentations at key conferences in endocrinology

ea0050p265 | Neuroendocrinology and Pituitary | SFEBES2017

Is 11C-methionine PET co-registered with MRI a game changer for persistent acromegaly?

Bhatt Dhruti , Shyamasunder Asha Hesarghatta , Sifontes-Dubon Mildred , Straiton Jack , Olson Shona , Kamel Mahmoud , Graveling Alex , Philip Sam , Abraham Prakash

Aims: 11C-methionine positron emission tomography co-registered with MRI (met-PET/MRI) is a new imaging technique used for functioning pituitary adenomas. In patients with persistent acromegaly after primary therapy, met-PET/MRI can help identify the site(s) of residual pituitary adenoma when MRI appearances are inconclusive and direct further targeted intervention (Trans-sphenoidal surgery-TSS or radiotherapy).<p class="ab...

ea0050p265 | Neuroendocrinology and Pituitary | SFEBES2017

Is 11C-methionine PET co-registered with MRI a game changer for persistent acromegaly?

Bhatt Dhruti , Shyamasunder Asha Hesarghatta , Sifontes-Dubon Mildred , Straiton Jack , Olson Shona , Kamel Mahmoud , Graveling Alex , Philip Sam , Abraham Prakash

Aims: 11C-methionine positron emission tomography co-registered with MRI (met-PET/MRI) is a new imaging technique used for functioning pituitary adenomas. In patients with persistent acromegaly after primary therapy, met-PET/MRI can help identify the site(s) of residual pituitary adenoma when MRI appearances are inconclusive and direct further targeted intervention (Trans-sphenoidal surgery-TSS or radiotherapy).<p class="ab...

ea0044p18 | Adrenal and Steroids | SFEBES2016

Primary adrenal insufficiency – establishing aetiology and screening for associated autoimmune diseases in a tertiary clinic

San Yap Pui , Gemma Rodriguez Carnero Maria , Hesarghatta Asha , Milne Alison , Graveling Alex , Philip Sam , Abraham Prakash

Aims: Recent Endocrine Society Guidelines (2016) suggest establishing the aetiology of primary adrenal insufficiency (PAI) and screening for other autoimmune conditions. The aim of our audit was to compare current practice against these recommendations.Methods: We identified patients seen in clinic over 18 months between January 2015 and May 2016. The data was collected by reviewing electronic and paper records.Results: Eighty-thre...

ea0094p237 | Neuroendocrinology and Pituitary | SFEBES2023

A post-operative fluid restriction protocol to reduce the incidence of delayed hyponatraemia following trans-sphenoidal pituitary surgery

Shyamasunder Asha Hesarghatta , Joseph Aneez , Kapoor Nitin , Paul Thomas , Thomas Nihal , Jebasingh Felix , Elizabeth Cherian Kripa , Rajan Remya , Prabhu Krishna , Chacko Ari , Christudoss Pamela , Jose Arun , Rebekah Grace

Delayed hyponatraemia(DH) is a well-known complication following trans-sphenoidal pituitary surgery (TSS), varying in incidence from 9–36% and occurs between post-operative days(POD) 4 to 14. Various studies have demonstrated that post-operative fluid restriction after TSS reduces the incidence of DH.Objective: to assess whether a fluid restriction protocol from POD5 to POD14 following TSS reduces the incidence of post-operative DH ...

ea0094p166 | Adrenal and Cardiovascular | SFEBES2023

Malignant pheochromocytoma and paraganglioma – clinical course and outcomes from a tertiary care centre in India

Rajan Remya , Asha Hesarghatta , Pai Rekha , Kapoor Nitin , Cherian Kripa , Paul Thomas , Jebasingh Felix , Thomas Nihal , Sigamani Elanthenral , Sathanam Prisca , MJ Paul , Cherian Anish , Thomas Shawn , Sen Supriya , Chandramohan Anuradha , Singh Ashish , Hepzhibah Julie , Kumar Santhosh , Gowri Mahasampath

Objectives: To study the clinical, biochemical, imaging profile and treatment outcomes of patients with malignant pheochromocytoma and paraganglioma(PPGL). Also, to compare their characteristics with non-malignant PPGL to identify the factors that may predict metastasis.Methods: This retropsective cohort study included 212 patients with PPGL managed at our centre over a period of 10 years(2013-2022). Their clinical, bioc...